Saracatinib

  • Chemical Properties
CAS No. 379231-04-6 Cat. No. BCP01733
Name Saracatinib
Synonyms AZD0530; AZD-0530;AZD 0530;
Formula C27H32ClN5O5 M. Wt 542.03
  • Biological Activity
Description Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival.
Related Products 893428-72-3(Saracatinib difumarate)
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Src/Bcr Abl 

Structure

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