BMS806

  • Chemical Properties
CAS No. 357263-13-9 Cat. No. BCP03050
Name BMS806
Synonyms BMS 806;BMS-806;BMS-378806;BMS 378806;BMS378806;
Formula C22H22N4O4 M. Wt 406.43
  • Biological Activity
Description BMS-806 (BMS 378806) was proved to be specific for HIV-1, with no activity against HIV-2 or simian immunodeficiency virus. BMS-806 (BMS 378806) is active against HIV-1 isolates irrespective of chemokine receptor preference. BMS-806 (BMS 378806) binds gp120, and changes in particular gp120 amino acid residues can alter the sensitivity of the virus to BMS-806 (BMS 378806). BMS-806 (BMS 378806) potently inhibited HIV-1 infection regardless of the particular chemokine receptor used.
Pathways Microbiology/Virology 
Targets HIV 

Structure

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