Meclizine dihydrochloride

  • Chemical Properties
CAS No. 1104-22-9 Cat. No. BCP02929
Name Meclizine dihydrochloride
Synonyms Meclizine 2HCl;Bonamine;Postafen;NSC28728;NSC-28728;NSC 28728;Parachloramine;
Formula C25H27ClN2.2HCl M. Wt 463.87
  • Biological Activity
Description Meclizine dihydrochloride is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness. Meclizine hydrochloride increases human pregnane X receptor (hPXR) target gene expression in human hepatocyte primary cultures.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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