CCT128930
| CAS No. | 885499-61-6 | Cat. No. | BCP02903 |
| Name | CCT128930 | ||
| Synonyms | CCT 128930;CCT-128930; | ||
| Formula | C18H20ClN5 | M. Wt | 341.84 |
| Description | CCT128930 exhibits marked antiproliferative activity against PTEN-deficient human tumor cell lines including U87MG human glioblastoma cells, LNCaP human prostate cancer cells and PC3 human prostate cancer cells with GI50 of 6.3 μM, 0.35 μM and 1.9 μM, respectively. Furthermore, CCT128930 causes a G1 arrest in PTEN-null U87MG human glioblastoma cells and Akt pathway blockade. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | AKT | ||
Structure
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