Cediranib

  • Chemical Properties
CAS No. 288383-20-0 Cat. No. BCP01378
Name Cediranib
Synonyms AZD2171;Recentin;AZD 2171;AZD-2171;
Formula C25H27FN4O3 M. Wt 450.51
  • Biological Activity
Description Cediranib, also known as AZD-2171, is a potent and selective VEGF inhibitor with antineoplastic activities. Competing with adenosine triphosphate, cediranib binds to and inhibits all three vascular endothelial growth factor receptor (VEGF-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets PDGFR VEGFR 

Structure

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