PF431396
| CAS No. | 717906-29-1 | Cat. No. | BCP01974 |
| Name | PF431396 | ||
| Synonyms | PF 431396;PF-431396; | ||
| Formula | C22H21F3N6O3S | M. Wt | 506.5 |
| Description | PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively). PF-431396 promotes osteoblast recruitment and activity, and stimulates bone formation in ovariectomized rats. PF-431396 is used in treatment of osteoporosis. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | FAK | ||
Structure
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