Telotristat ethyl
| CAS No. | 1033805-22-9 | Cat. No. | BCP02293 |
| Name | Telotristat ethyl | ||
| Synonyms | LX-1606;LX 1606;LX1606; | ||
| Formula | C27H26ClF3N6O3 | M. Wt | 574.98 |
| Description | Telotristat Ethyl is the ethyl ester form of telotristat, a tryptophan hydroxylase (TPH) inhibitor, with potential anti-serotonergic activity. Upon administration, telotristat binds to and inhibits the activity of TPH. This may result in a reduction in peripheral serotonin (5-HT) production and improvement of serotonin-mediated gastrointestinal effects such as severe diarrhea. TPH, the rate-limiting enzyme in serotonin biosynthesis, is overexpressed in carcinoid tumor cells. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Tryptophan Hydroxylase/TPH | ||
Structure
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