UK 383367

  • Chemical Properties
CAS No. 348622-88-8 Cat. No. BCP02332
Name UK 383367
Synonyms UK383367;UK-383367;
Formula C15H24N4O4 M. Wt 324.38
  • Biological Activity
Description UK-383367 is effective at penetrating human skin.UK-383367 inhibits collagen deposition with IC50 of ~2 μM. UK-383367 has modest affinity for all the PDE-4 subtypes PDE-4a, PDE-4b, PDE-4c and PDE-4d with IC50 of 1.8 μM, 1.5 μM, 2.4 μM and 0.9 μM, respectively.UK-383367 is a weakly acidic compound and lipophilic.
Pathways Protease/Metabolic Enzyme 
Targets Procollagen C Proteinase 

Structure

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