DMXAA
| CAS No. | 117570-53-3 | Cat. No. | BCP01949 |
| Name | DMXAA | ||
| Synonyms | ASA404; ASA 404; ASA-404; AS1404; AS 1404; AS-1404; Vadimezan; | ||
| Formula | C17H14O4 | M. Wt | 282.29 |
| Description | Combination of menadione and DMXAA leads to an increase in the antiproliferative activity of DLD-1 cells. DMXAA, as an antiviral agent, inhibits VSV-induced cytotoxicity and influenza virus replication in RAW 264.7 macrophages. A recent study shows that DMXAA has non-immune-mediated inhibitory effects against several kinase members of VEGFR (vascular endothelial growth factor receptor), such as VEGFR2 signalling in human umbilical vein endothelial cells. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Others Pathway | ||
| Targets | Interleukin Related STING VDA | ||
Structure
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