Sunitinib Malate
| CAS No. | 341031-54-7 | Cat. No. | BCP01768 |
| Name | Sunitinib Malate | ||
| Synonyms | SU 11248 Malate;SU11248 Malate;SU-11248 Malate; | ||
| Formula | C26H33FN4O7 | M. Wt | 532.56 |
| Description | Sunitinib Malate is the orally bioavailable malate salt of an indolinone-based tyrosine kinase inhibitor with potential antineoplastic activity. Sunitinib blocks the tyrosine kinase activities of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor b (PDGFRb), and c-kit, thereby inhibiting angiogenesis and cell proliferation. This agent also inhibits the phosphorylation of Fms-related tyrosine kinase 3 (FLT3), another receptor tyrosine kinase expressed by some leukemic cells. | ||
| Related Products | 557795-19-4（Sunitinib） | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | PDGFR VEGFR | ||
Structure
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