Lapatinib Ditosylate
| CAS No. | 388082-78-8 | Cat. No. | BCP01815 |
| Name | Lapatinib Ditosylate | ||
| Synonyms | Tykerb Ditosylate;GW572016 ditosylate; GW2016 ditosylate; | ||
| Formula | C29H26ClFN4O4S.2(C7H8O3S) | M. Wt | 925.46 |
| Description | Lapatinib Ditosylate is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. | ||
| Related Products | 231277-92-2（Lapatinib） 388082-77-7（Lapatinib ditosylate） | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR HER2 | ||
Structure
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