Neratinib

  • Chemical Properties
CAS No. 698387-09-6 Cat. No. BCP01870
Name Neratinib
Synonyms HKI-272;HKI272;HKI 272; PB272; PB 272; PB-272;
Formula C30H29ClN6O3 M. Wt 557.04
  • Biological Activity
Description Neratinib (HKI-272) is a tyrosine kinase inhibitor, it is a dual inhibitor of the human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway 
Targets EGFR HER2 

Structure

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