TG101348

  • Chemical Properties
CAS No. 936091-26-8 Cat. No. BCP02300
Name TG101348
Synonyms TG-101348;TG 101348;Fedratinib;SAR302503;SAR-302503;SAR 302503;
Formula C27H36N6O3S M. Wt 524.68
  • Biological Activity
Description Fedratinib is an oral selective inhibitor of Janus associated kinase 2 (JAK-2) and FMS-like tyrosine kinase 3 (FLT3) that is used in the therapy of intermediate or high-risk, primary or secondary myelofibrosis.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics 
Targets Epigenetic Reader Domain JAK 

Structure

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