DMH-1
| CAS No. | 1206711-16-1 | Cat. No. | BCP09856 |
| Name | DMH-1 | ||
| Synonyms | DMH1;DMH 1; | ||
| Formula | C24H20N4O | M. Wt | 380.44 |
| Description | DMH1 inhibits BMP signaling with IC50 of 100 nM, and selectively inhibits the BMP-induced Smad1/5/8 activation.DMH1 increases cardiomyocyte progenitors and promotes cardiac differentiation in mouse embryonic stem cells. In addition, DMH1, as a BMP inhibitor, significantly reduces NSCLC cell growth, migration and invasion. | ||
| Pathways | TGF beta/Smad | ||
| Targets | BMP/TGF beta Receptor | ||
Structure
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