Darusentan

  • Chemical Properties
CAS No. 171714-84-4 Cat. No. BCP13024
Name Darusentan
Synonyms LU-135252; LU 135252; HMR-4005;HMR4005;HMR 4005;LU135252;
Formula C22H22N2O6 M. Wt 410.42
  • Biological Activity
Description Darusentan is a selective endothelin-1 receptor A inhibitor. Darusentan is identified as the treatment of congestive heart failure, hypertension and cancers. It blocks endothelin ETA receptor thus results in an increase of sodium and potassium excretion in aging rats.
Pathways GPCR/G Protein 
Targets Endothelin Receptor 

Structure

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