Daclatasvir dihydrochloride

  • Chemical Properties
CAS No. 1009119-65-6 Cat. No. BCP13025
Name Daclatasvir dihydrochloride
Synonyms Daclatasvir 2HCl;BMS-790052 dihydrochloride;BMS790052 dihydrochloride;BMS 790052 dihydrochloride; EBP883; EBP 883; EBP-883;
Formula C40H52Cl2N8O6 M. Wt 811.8
  • Biological Activity
Description Daclatasvir is NS5A inhibitor and a drug for the treatment of hepatitis C (HCV). It is was developed by Bristol-Myers Squibb and was approved in Europe on 22 August 2014. Daclatasvir inhibits the HCV nonstructural protein NS5A. Recent research suggests that it targets two steps of the viral replication process, enabling rapid decline of HCV RNA. Daclatasvir has been tested in combination regimens with pegylated interferon and ribavirin, as well as with other direct-acting antiviral agents including asunaprevir and sofosbuvir.
Pathways Protease/Metabolic Enzyme Microbiology/Virology 
Targets HCV Protease HCV 

Structure

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