Itacitinib
| CAS No. | 1334298-90-6 | Cat. No. | BCP13794 |
| Name | Itacitinib | ||
| Synonyms | INCB39110;INCB-39110;INCB 39110; INCB039110; INCB-039110; INCB 039110; | ||
| Formula | C26H23F4N9O | M. Wt | 553.51 |
| Description | Itacitinib, also known as INCB39110 or INCB039110, is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis. INCB039110 produced significant improvements in sPGA, demonstrating proof of concept in chronic plaque psoriasis. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
| Targets | JAK | ||
Structure
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