SB-681323

  • Chemical Properties
CAS No. 444606-18-2 Cat. No. BCP23819
Name SB-681323
Synonyms SB 681323; SB681323; GW 681323; GW-681323; GW681323; Dilmapimod;
Formula C23H19F3N4O3 M. Wt 456.42
  • Biological Activity
Description SB-681323, also known as Dilmapimod and GW-681323 , is p38 MAPK inhibitor. SB-681323 inhibited the p38 MAPK pathway to a greater degree than prednisolone did. SB-681323 inhibited TNF-alpha production. SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in COPD. The treatment with SB-681832 is a safe and effective means of reducing hsCRP in patients undergoing elective PCI.
Pathways MAPK Pathway 
Targets p38 MAPK 

Structure

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