GRGDNP
| CAS No. | 114681-65-1 | Cat. No. | BCP15902 |
| Name | GRGDNP | ||
| Synonyms | glycyl-L-arginylglycyl-L-α-aspartyl-L-asparaginyl-L-proline； GRGDNP|H-Gly-Arg-Gly-Asp-Asn-Pro-OH； RGD Peptide; | ||
| Formula | C23H38N10O10 | M. Wt | 614.61 |
| Description | RGD peptide is a synthetic compound made up of the arginine-glycine-aspartate motif that has been extensively used to inhibit integrin-ligand interactions in studies related to cell adhesion， migration， growth， and differentiation. RGD peptide has also been shown to directly induce apoptosis， independent of integrin-mediated cell clustering or signals， by initiating conformational changes that enhance pro-caspase-3 activation and autoprocessing. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Apoptosis Pathway | ||
| Targets | Apoptosis Inducer Integrin | ||
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RGD-modified liposomes enhance efficiency of aclacinomycin A delivery: evaluation of their effect in lung cancer
Publications Citing of Biochempartner's GRGDNP(CAS:114681-65-1) |
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Preparation and evaluation of RGD and TAT co-modified docetaxel-loaded liposome
Publications Citing of Biochempartner's GRGDNP(CAS:114681-65-1) |
Structure
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