Pitolisant hydrochloride

  • Chemical Properties
CAS No. 903576-44-3 Cat. No. BCP16427
Name Pitolisant hydrochloride
Synonyms Ciproxidine;BF 2649;BF2649;BF-2649;
Formula C17H27Cl2NO M. Wt 332.31
  • Biological Activity
Description Pitolisant, also known as Tiprolisant, BF2649 and Ciproxidine, is a histamine receptor inverse agonist/antagonist selective for the H3 subtype. It has stimulant and nootropic effects in animal studies, and may have several medical applications, having been researched for the treatment of narcolepsy, for which it has been granted orphan drug status in the EU and US. It is currently in clinical trials for schizophrenia and Parkinson's disease. Pitolisant was the first clinically used H3 receptor inverse agonist.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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