SR13668

  • Chemical Properties
CAS No. 637774-61-9 Cat. No. BCP24033
Name SR13668
Synonyms SR 13668; SR-13668;
Formula C25H22N2O5 M. Wt 430.45
  • Biological Activity
Description SR13668 is an Akt inhibitor, is also a n orally bioavailable indole-3-carbinol (I3C) analogue inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic and antiangiogenic activities. Akt inhibitor SR13668 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation, and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.
Pathways PI3K/Akt/mTOR 
Targets AKT 

Structure

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