IQ-1S

  • Chemical Properties
CAS No. 23146-22-7 Cat. No. BCP17485
Name IQ-1S
Synonyms 11H-Indeno[1,2-b]quinoxalin-11-one oxime;IQ 1S free acid;
Formula C15H9N3O M. Wt 247.25
  • Biological Activity
Description IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis.
Pathways MAPK Pathway 
Targets JNK 

Structure

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