AC-DEVD-AFC

  • Chemical Properties
CAS No. 201608-14-2 Cat. No. BCP18218
Name AC-DEVD-AFC
Synonyms N-Acetyl-Asp-Glu-Val-Asp-7-amino-4-Trifluoromethylcoumarin; Caspase-3 Substrate (Fluorogenic);
Formula C30H34F3N5O13 M. Wt 729.61
  • Biological Activity
Description Ac-DEVD-AFC is a fluorogenic substrate for caspase-3 and related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
Pathways Protease/Metabolic Enzyme Apoptosis Pathway 
Targets Caspase 

Structure

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