Miransertib
| CAS No. | 1313881-70-7 | Cat. No. | BCP19821 |
| Name | Miransertib | ||
| Synonyms | AKT inhibitor 2;ARQ092;ARQ 092;ARQ-092; | ||
| Formula | C27H24N6 | M. Wt | 432.52 |
| Description | ARQ-092, also called as Miransertib, is an oral activie, potent and selective AKT inhibitor with IC50= 5.0 nM against AKT1, 4.5 nM against AKT2 and 16 nM against AKT3. ARQ-092 inhibits the PI3K/AKT signaling pathway due to inhibition of the activity of AKT in a non-ATP competitive manner. This may lead to the reduction in tumor cell proliferation and the induction of tumor cell apoptosis. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | AKT | ||
Structure
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