Daclatasvir

  • Chemical Properties
CAS No. 1009119-64-5 Cat. No. BCP02431
Name Daclatasvir
Synonyms BMS790052; EBP-883; EBP 883; EBP883;BMS 790052;BMS790052; Daklinza;
Formula C40H50N8O6 M. Wt 738.89
  • Biological Activity
Description Daclatasvir is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to treat chronic hepatitis C. Elevations in serum enzyme levels during daclatasvir therapy are uncommon, and it has yet to be convincingly implicated in cases of clinically apparent liver injury with jaundice. Nevertheless, and for unknown reasons, successful all-oral regimens of antiviral therapy in patients with chronic hepatitis C and cirrhosis is occasionally complicated by hepatic decompensation and may cause reactivation of hepatitis B in susceptible patients coinfected with the hepatitis B virus (HBV).
Pathways Protease/Metabolic Enzyme Microbiology/Virology 
Targets HCV Protease HCV 
  • Publications Citing

Structure

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