达卡他韦
| CAS号 | 1009119-64-5 | 货号 | BCP02431 |
| 中文名 | 达卡他韦 | ||
| 英文名 | Daclatasvir | ||
| 中文别名 | 达卡拉韦; 达拉他韦; | ||
| 英文别名 | BMS790052; EBP-883; EBP 883; EBP883;BMS 790052;BMS790052; Daklinza; | ||
| 分子式 | C40H50N8O6 | 分子量 | 738.89 |
| 生物活性 | Daclatasvir is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to treat chronic hepatitis C. Elevations in serum enzyme levels during daclatasvir therapy are uncommon, and it has yet to be convincingly implicated in cases of clinically apparent liver injury with jaundice. Nevertheless, and for unknown reasons, successful all-oral regimens of antiviral therapy in patients with chronic hepatitis C and cirrhosis is occasionally complicated by hepatic decompensation and may cause reactivation of hepatitis B in susceptible patients coinfected with the hepatitis B virus (HBV). | ||
| 信号通路 | Protease/Metabolic Enzyme Microbiology/Virology | ||
| 靶 点 | HCV Protease HCV | ||
|
Different Interaction Profiles of Direct-Acting Anti-Hepatitis C Virus Agents with Human Organic Anion Transporting Polypeptides
购于瀚香生物(Biochempartner)的达卡他韦(CAS:1009119-64-5)被引用 |
结构式
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