Trichostatin A

CAS No.	58880-19-6	Cat. No.	BCP01776
Name	Trichostatin A
Synonyms	TSA; (+)-Trichostatin A; Trichostatin A (R-isomer);
Formula	C17H22N2O3	M. Wt	302.37

Description	Trichostatin A, also known as TSA, is a HDAC inhibitor. TSA inhibits the eukaryotic cell cycle during the beginning of the growth stage. TSA can be used to alter gene expression by interfering with the removal of acetyl groups from histones (histone deacetylases, HDAC) and therefore altering the ability of DNA transcription factors to access the DNA molecules inside chromatin. It is a member of a larger class of histone deacetylase inhibitors (HDIs or HDACIs) that have a broad spectrum of epigenetic activities. TSA inhibits HDACs 1, 3, 4, 6 and 10 with IC50 values around 20 nM.
Pathways	Cell Cycle/DNA Damage Epigenetics
Targets	HDAC

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.

For product details of different batches, please contact our Customer

Products are for research use only and not for human use. We do not sell to patients.