PRN1371

  • Chemical Properties
CAS No. 1802929-43-6 Cat. No. BCP20493
Name PRN1371
Synonyms PRN-1371; PRN 1371;
Formula C26H30Cl2N6O4 M. Wt 561.46
  • Biological Activity
Description PRN-1371 is a covalent, irreversible, highly selective FGFR1, 2, 3 and 4 inhibitor. PRN1371 inhibits all four FGFR isoforms and blocks aberrant FGFR kinase signaling. This broad profile is suitable to treat many tumor types, including but not limited to urothelial, squamous lung, gastric and hepatocellular carcinoma
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets FGFR 

Structure

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