MK-8617
| CAS No. | 1187990-87-9 | Cat. No. | BCP25371 |
| Name | MK-8617 | ||
| Synonyms | MK 8617;MK8617; | ||
| Formula | C24H21N5O4 | M. Wt | 443.46 |
| Description | MK-8617 is a potent, selective, orally bioavailabl Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1−3 (HIF PHD1−3) for the Treatment of Anemia (PHD2 IC50 = 1.0 nM; 10-19 hr dog and moneky t1/2). Anemia is a condition of insufficient red blood cells (RBCs) or hemoglobin (Hb) levels that result in reduced functional capability, fatigue, and shortness of breath. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | HIF | ||
Structure
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