AZ9482
| CAS No. | 1825345-33-2 | Cat. No. | BCP20636 |
| Name | AZ9482 | ||
| Synonyms | AZ-9482; AZ 9482; | ||
| Formula | C26H22N6O2 | M. Wt | 450.50 |
| Description | AZ9482, a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18 nM). Encouragingly, AZ9482 also showed a 3 nM GI50 in the DLBCL cell line OCI-LY-19 in a 3-day AlamarBlue assay. Consistent with published siRNA knockdown experiments, AZ9482 was a 9 nM enzyme inhibitor of tankyrase 1 (TNKS1). | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | PARP | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.