Bisindoylmaleimide X

  • Chemical Properties
CAS No. 1241725-89-2 Cat. No. BCP25395
Name Bisindoylmaleimide X
Synonyms Ro 31-8425;Ro 318425;3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-2-yl)pyrrole-2,5-dione;
Formula C26H24N4O2 M. Wt 424.504
  • Biological Activity
Description Bisindolylmaleimide X is a cell-permeable, reversible, ATP-competitive protein kinase C (PKC) inhibitor (IC50 = 15 nM, rat brain PKC).
Pathways TGF beta/Smad  Epigenetics 
Targets PKC 

Structure

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