CEP-33779
CAS No. | 1346168-57-7 | Cat. No. | BCP20654 |
Name | CEP-33779 | ||
Synonyms | |||
Formula | C24H26N6O2S | M. Wt | 462.57 |
Description | Soluble in DMSO or ethanol. CEP-33779 is a highly selective, orally active inhibitor for JAK2 with an IC(50) of 1.8nM in enzyme and 61nM in cell activity. It inhibits JAK3 with an IC(50) of 150nM. Target: JAK | Kinase Group: PTK | Substrate: Tyrosine | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
Targets | JAK |
Structure
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