CEP-33779

  • Chemical Properties
CAS No. 1346168-57-7 Cat. No. BCP20654
Name CEP-33779
Synonyms
Formula C24H26N6O2S M. Wt 462.57
  • Biological Activity
Description Soluble in DMSO or ethanol. CEP-33779 is a highly selective, orally active inhibitor for JAK2 with an IC(50) of 1.8nM in enzyme and 61nM in cell activity. It inhibits JAK3 with an IC(50) of 150nM. Target: JAK | Kinase Group: PTK | Substrate: Tyrosine
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics 
Targets JAK 

Structure

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