KW-2449 HCl
CAS No. | 841259-17-4 | Cat. No. | BCP20681 |
Name | KW-2449 HCl | ||
Synonyms | |||
Formula | C20H21ClN4O | M. Wt | 368.86 |
Description | KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC(50) of 6.6nM, modestly potent to FGFR1, Bcr-Abl and Aurora A, little effect on PDGFRbeta, IGF-1R, EGFR. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase Cell Cycle/DNA Damage Epigenetics | ||
Targets | Src/Bcr Abl Aurora FLT3 FGFR |
Structure
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