Resibufogenin

  • Chemical Properties
CAS No. 465-39-4 Cat. No. BCP20705
Name Resibufogenin
Synonyms RBG; Bufotenine;
Formula C24H32O4 M. Wt 384.51
  • Biological Activity
Description Resibufogenin is a cardiac glycoside first isolated from Bufonis venom that acts as an inhibitor of the Na+/K+-ATPase.It exhibits cardiotonic, vasopressor, and respiratory stimulating actions in both animal and clinical models.Resibufogenin has been used to antagonize the action of marinobufagenin in a rat experimental model of preeclampsia. Resibufogenin is also reported to have antiproliferative effects against cancer cells, inducing cell cycle arrest by suppressing the expression of cyclin D1.
Pathways Others Pathway 
Targets Others 

Structure

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