Sch 23390 hydrochloride
CAS No. | 125941-87-9 | Cat. No. | BCP20717 |
Name | Sch 23390 hydrochloride | ||
Synonyms | Sch 23390 hydrochloride; | ||
Formula | C17H18ClNOHCl | M. Wt | 324.24 |
Description | Potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively). Blocks quinpirole-induced Kir3 (GIRK) currents (EC50 = 268 nM) independently of receptors. | ||
Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
Targets | Dopamine Receptor |
Structure
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