Sch 23390 hydrochloride

  • Chemical Properties
CAS No. 125941-87-9 Cat. No. BCP20717
Name Sch 23390 hydrochloride
Synonyms Sch 23390 hydrochloride;
Formula C17H18ClNOHCl M. Wt 324.24
  • Biological Activity
Description Potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively). Blocks quinpirole-induced Kir3 (GIRK) currents (EC50 = 268 nM) independently of receptors.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Dopamine Receptor 

Structure

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