ZK-756326
| CAS No. | 874911-96-3 | Cat. No. | BCP20725 |
| Name | ZK-756326 | ||
| Synonyms | ZK 756326;ZK756326; | ||
| Formula | C21H28N2O3 | M. Wt | 356.47 |
| Description | ZK 756326 is a selective, non-peptide CKR-8 (CCR8 chemokine receptor) agonist (IC50 values are 1.8 and 2.6μM for human and mouse receptors respectively). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion. ZK 756326 displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs.Selective, non-peptide CCR8 chemokine receptor agonist (IC50 values are 1.8 and 2.6 μM for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CCR | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.