4-P-PDOT
CAS No. | 134865-74-0 | Cat. No. | BCP20763 |
Name | 4-P-PDOT | ||
Synonyms | 4-Phenyl-2-propionamidotetralin; 4p-PDOT; 4PPDOT; 4P-PDOT; AH-024; 4-phenyl-2- propionamidotetralin; | ||
Formula | C19H21NO | M. Wt | 279.38 |
Description | 4-P-PDOT is an antagonist of the melatonin 2 (MT2) receptor (pKi = 8.37) that displays 60-fold selectivity for MT2 over MT1. 4-P-PDOT is used in cells, explants, and animals to elucidate the role of MT2 in melatonin-mediated signaling. | ||
Pathways | GPCR/G Protein | ||
Targets | Melatonin Receptor |
Structure
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