4-P-PDOT

  • Chemical Properties
CAS No. 134865-74-0 Cat. No. BCP20763
Name 4-P-PDOT
Synonyms 4-Phenyl-2-propionamidotetralin; 4p-PDOT; 4PPDOT; 4P-PDOT; AH-024; 4-phenyl-2- propionamidotetralin;
Formula C19H21NO M. Wt 279.38
  • Biological Activity
Description 4-P-PDOT is an antagonist of the melatonin 2 (MT2) receptor (pKi = 8.37) that displays 60-fold selectivity for MT2 over MT1. 4-P-PDOT is used in cells, explants, and animals to elucidate the role of MT2 in melatonin-mediated signaling.
Pathways GPCR/G Protein 
Targets Melatonin Receptor 

Structure

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