GAL-021
| CAS No. | 1380341-99-0 | Cat. No. | BCP20772 |
| Name | GAL-021 | ||
| Synonyms | GAL-021; | ||
| Formula | C11H22N6O | M. Wt | 254.33 |
| Description | GAL-021 is a large conductance calcium-activated potassium channel (BKCa-channel) blocker potentially for the treatment of respiratory depression. GAL-021 inhibited KCa1.1 in GH3 cells, and the evoked ventilatory stimulation was attenuated in Slo1 mice lacking the pore-forming α-subunit of the KCa1.1 channel. At a higher concentration of GAL-160 (100 μM), inhibition of the delayed rectifier K(+) current and leak K(+) current were observed. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel | ||
Structure
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