RG-14620
| CAS No. | 136831-49-7 | Cat. No. | BCP20770 |
| Name | RG-14620 | ||
| Synonyms | RG14620; RG-14620; TYRPHOSTIN RG 14620; | ||
| Formula | C14H8Cl2N2 | M. Wt | 275.13 |
| Description | RG-14620 is an EGFR inhibitor. It is a non-phenolic tyrphostin analog, which is selective for the EGF receptor and long acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=3 μM) as well as tumor growth in vivo. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR | ||
Structure
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