Y16
| CAS No. | 429653-73-6 | Cat. No. | BCP25513 |
| Name | Y16 | ||
| Synonyms | RhoA-IN-Y16; Y-16; Y 16; | ||
| Formula | C24H20N2O3 | M. Wt | 384.43 |
| Description | Y16, also known as RhoA-IN-Y16, is a RhoA inhibitor, Y16 blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM). Y16 specifically inhibits LARG catalyzed activation of RhoA and RhoA signaling pathways. Y16 blocks the growth and migration of MCF7 breast cancer cells. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Ras/Rho | ||
Structure
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