SU 4312
| CAS No. | 5812-07-7 | Cat. No. | BCP20743 |
| Name | SU 4312 | ||
| Synonyms | SU-4312; SU4312. DMBI; NSC 86429; NSC-86429; NSC86429; | ||
| Formula | C17H16N2O | M. Wt | 264.32 |
| Description | SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | PDGFR VEGFR | ||
Structure
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