ML240
| CAS No. | 1346527-98-7 | Cat. No. | BCP25527 |
| Name | ML240 | ||
| Synonyms | ML 240;ML-240; | ||
| Formula | C23H20N6O | M. Wt | 396.45 |
| Description | ML240 is a ATP-competitive inhibitor of p97 ATPase (IC50 = 110 nM). p97 is a homohexamer with each protomer containing a protein−protein interaction domain at the N-terminus, a D1 ATPase/hexamerization domain, and the catalytic D2 ATPase domain. p97 inhibitors could have improved therapeutic potential in tumor types currently treated by proteasome inhibitors. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | p97 | ||
Structure
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