EPZ031686

  • Chemical Properties
CAS No. 1808011-22-4 Cat. No. BCP20778
Name EPZ031686
Synonyms EPZ-031686; EPZ 031686;
Formula C26H34ClF3N4O4S M. Wt 591.09
  • Biological Activity
Description EPZ031686 is a potent and selective SMYD3 inhibitor. EPZ031686 shows good bioavailability following oral dosing in mice making it a suitable tool for potential in vivo target validation studies. SMYD3 has been implicated in a range of cancers; however, until now no potent selective small molecule inhibitors have been available for target validation studies.
Pathways Epigenetics 
Targets Histone Methyltransferase 

Structure

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