BGB290

  • Chemical Properties
CAS No. 1446261-44-4 Cat. No. BCP20780
Name BGB290
Synonyms Pamiparib;BGB-290;BGB 290;
Formula C16H15FN4O M. Wt 298.31
  • Biological Activity
Description Pamiparib(BGB-290) is a highly potent and selective PARP inhibitor with favorable drug metabolism and pharmacokinetic properties. BGB-290 has shown favorable PARP1 and PARP2 selectivity in biochemical assays and has demonstrated improved specificity compared to other PARP inhibitors, such as olaparib, in cell line proliferation screens.
Pathways Cell Cycle/DNA Damage Epigenetics 
Targets PARP 

Structure

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