BGB290
CAS No. | 1446261-44-4 | Cat. No. | BCP20780 |
Name | BGB290 | ||
Synonyms | Pamiparib;BGB-290;BGB 290; | ||
Formula | C16H15FN4O | M. Wt | 298.31 |
Description | Pamiparib(BGB-290) is a highly potent and selective PARP inhibitor with favorable drug metabolism and pharmacokinetic properties. BGB-290 has shown favorable PARP1 and PARP2 selectivity in biochemical assays and has demonstrated improved specificity compared to other PARP inhibitors, such as olaparib, in cell line proliferation screens. | ||
Pathways | Cell Cycle/DNA Damage Epigenetics | ||
Targets | PARP |
Structure
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