Delpazolid
CAS No. | 1219707-39-7 | Cat. No. | BCP25650 |
Name | Delpazolid | ||
Synonyms | LCB01-0371; LCB 01-0371; LCB-01-0371; LCB010371; LCB 010371; LCB-010371; | ||
Formula | C14H17FN4O3 | M. Wt | 308.31 |
Description | Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus. | ||
Pathways | Microbiology/Virology | ||
Targets | Antibiotic |
Structure
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