普可那利
| CAS号 | 153168-05-9 | 货号 | BCP20819 |
| 中文名 | 普可那利 | ||
| 英文名 | Pleconaril | ||
| 中文别名 | |||
| 英文别名 | SR-263843; SR-63843; VP-63843; Win-63843; SR263843; SR63843; VP63843; Win63843; SR 263843; SR 63843; VP 63843; Win 63843; | ||
| 分子式 | C18H18F3N3O3 | 分子量 | 381.35 |
| 生物活性 | Pleconaril is an antiviral drug potentially for the treatment of enterovirus infection and asthma. Pleconaril, administered either orally or intranasally, is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus.It has shown useful activity against the dangerous strain enterovirus D68. Pleconaril binds to a hydrophobic pocket in the VP1 protein. Pleconaril has been shown in viral assembly to associate with viral particles.[9] Through noncovalent, hydrophobic interactions compounds can bind to the hydrophobic pocket. Amino acids in positions Tyr152 and Val191 are a part of the VP1 drug binding pocket. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | Enterovirus | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！