LY-2510924

  • Chemical Properties
CAS No. 1088715-84-7 Cat. No. BCP20800
Name LY-2510924
Synonyms LY2510924 ; LY 2510924;
Formula C62H87N13O11 M. Wt 1190.46
  • Biological Activity
Description LY2510924 is an inhibitor of CXC chemokine receptor 4 (CXCR4), with potential antineoplastic activity. Upon subcutaneous administration, CXCR4 inhibitor LY2510924 binds to the chemokine receptor CXCR4, thereby preventing CXCR4 binding to its ligand, stromal derived factor-1 (SDF-1), and subsequent receptor activation. This may result in decreased tumor cell proliferation and migration. CXCR4, a chemokine receptor belonging to the G protein-coupled receptor (GPCR) gene family, plays an important role in chemotaxis and angiogenesis and is upregulated in several tumor cell types.
Pathways GPCR/G Protein 
Targets CXCR 

Structure

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