JNJ-64619178

  • Chemical Properties
CAS No. 2086772-26-9 Cat. No. BCP25732
Name JNJ-64619178
Synonyms JNJ 64619178; JNJ64619178;
Formula C22H23BrN6O2 M. Wt 483.36
  • Biological Activity
Description JNJ-64619178 is a PRMT5 inhibitor with high selectivity and potency (subnanomolar range, PRMT5-MEP-50 IC50=0.14 nM) under different in vitro and cellular conditions, paired with favorable pharmacokinetics and safety properties.
Pathways Epigenetics 
Targets Histone Methyltransferase 

Structure

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