JNJ-64619178
CAS No. | 2086772-26-9 | Cat. No. | BCP25732 |
Name | JNJ-64619178 | ||
Synonyms | JNJ 64619178; JNJ64619178; | ||
Formula | C22H23BrN6O2 | M. Wt | 483.36 |
Description | JNJ-64619178 is a PRMT5 inhibitor with high selectivity and potency (subnanomolar range, PRMT5-MEP-50 IC50=0.14 nM) under different in vitro and cellular conditions, paired with favorable pharmacokinetics and safety properties. | ||
Pathways | Epigenetics | ||
Targets | Histone Methyltransferase |
Structure
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