CCT251236
CAS No. | 1693731-40-6 | Cat. No. | BCP20805 |
Name | CCT251236 | ||
Synonyms | |||
Formula | C32H32N4O5 | M. Wt | 552.62 |
Description | CCT251236 is a potent and orally active Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen. CCT251236 is orally bioavailable and displays efficacy in a human ovarian carcinoma xenograft model. CCT251236 demonstrated excellent antiproliferative activity against the WM266.4 cell line (pGI50 = 7.92 ± 0.10, GI50 = 12 nM, n =11). | ||
Pathways | Protease/Metabolic Enzyme Cell Cycle/DNA Damage | ||
Targets | HSP |
Structure
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