CCT251236

  • Chemical Properties
CAS No. 1693731-40-6 Cat. No. BCP20805
Name CCT251236
Synonyms
Formula C32H32N4O5 M. Wt 552.62
  • Biological Activity
Description CCT251236 is a potent and orally active Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen. CCT251236 is orally bioavailable and displays efficacy in a human ovarian carcinoma xenograft model. CCT251236 demonstrated excellent antiproliferative activity against the WM266.4 cell line (pGI50 = 7.92 ± 0.10, GI50 = 12 nM, n =11).
Pathways Protease/Metabolic Enzyme Cell Cycle/DNA Damage 
Targets HSP 

Structure

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