BI 882370
| CAS No. | 1392429-79-6 | Cat. No. | BCP20821 |
| Name | BI 882370 | ||
| Synonyms | BI-882370; BI882370; | ||
| Formula | C28H33F2N7O2S | M. Wt | 569.68 |
| Description | BI 882370 is a highly potent and selective RAF inhibitor that binds to the DFG-out (inactive) conformation of the BRAF kinase. BI 882370 inhibits proliferation of human BRAF-mutant melanoma cells with 100× higher potency (1-10 nmol/L) than vemurafenib. | ||
| Pathways | MAPK Pathway | ||
| Targets | Raf | ||
Structure
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